What will study participants be asked to do?

As a study participant you will be asked to:

• Attend 15 study visits during an 83-week period
• Receive six infusions of the investigational drug every 13 weeks for 65 weeks
• Have blood tests and study-related physical and clinical exams

Participants will be randomized to investigational product or placebo (a treatment with no active ingredient). There is a 60 percent chance of receiving the investigational drug and a 40 percent chance of receiving a placebo.

• What is the ICARA study?
• Who can participate?
• How can participants benefit?
• What will participants be asked to do?
• See if you may be eligible
• Where can I enroll?
• For study information outside the
       United States and Canada