Alzheimer’s Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research
Dementia and cancer are becoming increasingly common in Western countries. In the last two decades, research has focused on Alzheimer’s disease (AD) and cancers, particularly, breast cancer (BC) and prostate cancer (PC), has been substantially funded both in Europe and worldwide.
While the results of scientific research have contributed to improving our understanding of disease etiopathology, still the prevalence of chronic degenerative conditions are still very high in the whole world. By definition, there is the perfect model. In particular, the animal model of AD, BC, and the PC has been and still is traditionally used in basic research / fundamental, translational and preclinical to study human disease mechanisms, identifying new therapeutic targets and develop new drugs
However, inadequate animal models of several important features of the human disease; Therefore, they often can not pave the way for the development of effective drugs in human patients. The emergence of new tools and models of technology in the life sciences, and the growing need for a multidisciplinary approach has prompted many interdisciplinary research initiatives. With substantial funds invested in biomedical research, it is becoming necessary to define and implement indicators to monitor contributions to innovation and impact of funded research.
Here, we discuss some of the issues underlying the failure of translation in AD, BC, and research PCs, and illustrates how the indicators can be applied to the output size and the impact of the retrospective funded biomedical research.
Disease coronavirus 19 (COVID-19) has dramatically changed daily life, including the field of research of the disease (AD) Alzheimer’s. This perspective article discusses some of the ways in which COVID-19 has impacted the field, anticipating some long-lasting effects, and explore strategies to address the needs of current and future. Areas of impact include the integrity of the study, regulatory issues and industry, and the involvement of the participants.
The proposed strategy to address these challenges include the analytical method to handle large degree lost data and development, user-friendly, means of data collection and remote patient-centered assessments. We also highlight the importance of maintaining the welfare of participants as a first priority and constant.

Synaptosome as a tool in the study of Alzheimer’s disease
synaptic dysfunction is an integral feature of the disease (AD) pathophysiology of Alzheimer’s. In fact, the prodromal manifestations of structural and functional deficits in synaptic much before the appearance of overt disease indicates that pathological hallmarks of AD may be regarded as a degenerative disorder of synapses.
Some research instruments and techniques have allowed us to study synaptic function and plasticity and their changes in pathological conditions, such as AD. One such tool is the biochemical preparation isolated from apart and resealed synaptic terminal, the “synaptosomes”. Due to the preservation of many physiological processes such as metabolism and enzymatic activity, synaptosomes has proven to be an ex vivo model of system is needed for the study of synaptic physiology either when isolated from fresh or cryopreserved tissue, and from animal or human post-mortem tissue.
Total RNA from Alzheimer's Disease: Occipital Lobe |
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R1236062Alz-10 | Biochain | 10 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Parietal Lobe |
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R1236066Alz-10 | Biochain | 10 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Postcentral Gyrus |
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R1236072Alz-10 | Biochain | 10 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Precentral Gyrus |
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R1236073Alz-10 | Biochain | 10 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Temporal Lobe |
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R1236078Alz-10 | Biochain | 10 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Pons |
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C1236071Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Pons |
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T1236071Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Total Protein from Alzheimer's Disease: Brain |
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P1236035Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Parkinson's Disease: Brain: Pons |
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P1236071Par | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Amygdala |
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P1236036Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Cerebellum |
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P1236039Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Hippocampus |
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P1236052Alz | Biochain | 1 mg | EUR 556 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Thalamus |
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P1236079Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Multiple Sclerosis Disease: Brain: Pons |
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P1236071Msc | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Corpus Callosum |
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P1236045Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Frontal Lobe |
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P1236051Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Medulla oblongata |
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P1236057Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Occipital Lobe |
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P1236062Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Parietal Lobe |
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P1236066Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Postcentral Gyrus |
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P1236072Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Precentral Gyrus |
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P1236073Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total Protein from Alzheimer's Disease: Brain: Temporal Lobe |
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P1236078Alz | Biochain | 1 mg | EUR 461 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Genomic DNA from Alzheimer's Disease: Brain: Pons, from a single donor |
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D1236071Alz | Biochain | 50 ug | EUR 446 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Colon |
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R1236090Dia-50 | Biochain | 50 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Esophagus |
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R1236106Dia-50 | Biochain | 50 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Pancreas |
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R1236188Dia-50 | Biochain | 50 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Stomach |
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R1236248Dia-50 | Biochain | 50 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Human Adult Normal Tissue: Brain: Pons |
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R1234071-10 | Biochain | 10 ug | EUR 194 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Amygdala (Alzheimer's Disease) Lysate |
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XBL-10274 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human amygdala tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human amygdala tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the amygdala tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The amygdala tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Hippocampus (Alzheimer's Disease) Lysate |
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XBL-10286 | ProSci | 0.1 mg | EUR 768.5 |
Description: Human hippocamps tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human hippocamps tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the hippocamps tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The hippocamps tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Thalamus (Alzheimer's Disease) Lysate |
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XBL-10310 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human thalamus tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human thalamus tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the thalamus tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The thalamus tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Total RNA from Congenital heart disease: Heart |
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R1236122Hd-3 | Biochain | 50 ug | EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Human Alzheimer's Disease Primer Library |
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HAZD-I | Real Time Primers | 1 set | EUR 548 |
cDNA from Alzheimer's Disease: Brain |
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C1236035Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Amygdala (Alzheimer's Disease) Membrane Lysate |
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XBL-10272 | ProSci | 0.1 mg | EUR 626.75 |
Description: Human brain amygdala tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human amygdala tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated brain amygdala tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated brain amygdala tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal. |
Corpus Callosum (Alzheimer's Disease) Lysate |
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XBL-10278 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human corpus Callosum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human corpus Callosum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the corpus Callosum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The corpus Callosum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Frontal Lobe (Alzheimer's Disease) Lysate |
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XBL-10282 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human frontal lobe tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human frontal lobe tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the frontal lobe tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The frontal lobe tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Hippocampus (Alzheimer's Disease) Cytoplasmic Lysate |
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XBL-10283 | ProSci | 0.1 mg | EUR 227.75 |
Description: Human brain hippocamps tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The human hippocamps tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated brain hippocamps tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated brain hippocamps tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot. |
Hippocampus (Alzheimer's Disease) Membrane Lysate |
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XBL-10284 | ProSci | 0.1 mg | EUR 710.75 |
Description: Human brain hippocamps tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human hippocamps tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated brain hippocamps tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated brain hippocamps tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal. |
Occipital lobe (Alzheimer's Disease) Lysate |
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XBL-10290 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human occipital lobe tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human occipital lobe tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the occipital lobe tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The occipital lobe tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Parietal Lobe (Alzheimer's Disease) Lysate |
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XBL-10294 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human parietal lobe tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human parietal lobe tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the parietal lobe tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The parietal lobe tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Postcentral Gyrus (Alzheimer's Disease) Lysate |
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XBL-10302 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human postcentral gyrus tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human postcentral gyrus tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the postcentral gyrus tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The postcentral gyrus tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Precentral Gyrus (Alzheimer's Disease) Lysate |
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XBL-10306 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human precentral gyrus tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human precentral gyrus tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the precentral gyrus tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The precentral gyrus tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Temporal Lobe (Alzheimer's Disease) Lysate |
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XBL-10314 | ProSci | 0.1 mg | EUR 663.5 |
Description: Human temporal lobe tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human temporal lobe tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the temporal lobe tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The temporal lobe tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Frozen Tissue Section - Parkinson's Disease: Brain: Pons |
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T1236071Par | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Alzheimers Disease: Brain: Pons |
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T2236071Alz | Biochain | 5 slides | EUR 257 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Parkinson's Disease: Brain: Pons |
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T2236071Par | Biochain | 5 slides | EUR 257 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
cDNA from Alzheimer's Disease: Brain: Amygdala |
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C1236036Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Cerebellum |
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C1236039Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Hippocampus |
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C1236052Alz | Biochain | 40 reactions | EUR 801 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Thalamus |
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C1236079Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Frozen Tissue Section - Alzheimer's Disease: Brain |
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T1236035Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Temporal Lobe (Alzheimer's Disease) Membrane Lysate |
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XBL-10312 | ProSci | 0.1 mg | EUR 626.75 |
Description: Human brain temporal lobe tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human temporal lobe tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated brain temporal lobe tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated brain temporal lobe tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal. |
Frozen Tissue Section - Multiple Sclerosis Disease: Brain: Pons |
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T1236071Msc | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Pons |
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T2236071Msc | Biochain | 5 slides | EUR 257 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Non-Ab Component of Alzheimer's Disease Amyloid |
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5-01639 | CHI Scientific | 4 x 1mg | Ask for price |
Non-Ab Component of Alzheimer's Disease Amyloid |
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SP-89317-1 | Alpha Diagnostics | 1 mg | EUR 286 |
cDNA from Alzheimer's Disease: Brain: Frontal Lobe |
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C1236051Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Occipital Lobe |
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C1236062Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Parietal Lobe |
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C1236066Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Postcentral Gyrus |
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C1236072Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Precentral Gyrus |
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C1236073Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Alzheimer's Disease: Brain: Temporal Lobe |
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C1236078Alz | Biochain | 40 reactions | EUR 668 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Amygdala |
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T1236036Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Cerebellum |
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T1236039Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Hippocampus |
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T1236052Alz | Biochain | 5 slides | EUR 821 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Pituitary |
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T1236068Alz | Biochain | 5 slides | EUR 821 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Thalamus |
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T1236079Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Alzheimer's Disease: Brain: Cerebellum |
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T2236039Alz | Biochain | 5 slides | EUR 257 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Total Protein from Progressive Supranuclear Palsy: Brain: Pons |
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P1236071PSP | Biochain | 1 mg | EUR 556 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Human Total PSA (t-PSA) ELISA Kit |
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PRB-5049-TOTAL | Cell Biolabs | 96 assays | EUR 572 |
Frozen Tissue Section - Alzheimer's Disease: Brain: Corpus Callosum |
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T1236045Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Frontal Lobe |
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T1236051Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Medulla oblongata |
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T1236057Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Occipital Lobe |
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T1236062Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Parietal Lobe |
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T1236066Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Postcentral Gyrus |
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T1236072Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Precentral Gyrus |
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T1236073Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Frozen Tissue Section - Alzheimer's Disease: Brain: Temporal Lobe |
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T1236078Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Alzheimer's Disease: Brain: Medulla oblongata |
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T2236057Alz | Biochain | 5 slides | EUR 465 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Crohn's Disease Exosome RNA |
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P241-CR | 101Bio | - | Ask for price |
Total Protein from Human Adult Normal Tissue: Brain: Pons |
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P1234071 | Biochain | 1 mg | EUR 214 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Green RNA Lysis Kit 50 |
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GREENE1-RNA | Next Advance | 50pack | EUR 180 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
Green RNA Lysis Kit 250 |
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GREENE5-RNA | Next Advance | 250pack | EUR 571 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
Pink RNA Lysis Kit 50 |
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PINKE1-RNA | Next Advance | 50pack | EUR 178 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Pink RNA Lysis Kit 250 |
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PINKE5-RNA | Next Advance | 250pack | EUR 561 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Navy RNA Lysis Kit 50 |
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NAVYE1-RNA | Next Advance | 50pack | EUR 198 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Navy RNA Lysis Kit 250 |
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NAVYE5-RNA | Next Advance | 250pack | EUR 651 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Red RNA Lysis Kit 50 |
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REDE1-RNA | Next Advance | 50pack | EUR 192 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Red RNA Lysis Kit 250 |
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REDE5-RNA | Next Advance | 250pack | EUR 622 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RNA Lysis Kit 50 |
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YELLOWE1-RNA | Next Advance | 50pack | EUR 192 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RNA Lysis Kit 250 |
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YELLOWE5-RNA | Next Advance | 250pack | EUR 624 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
RNA isolater Total RNA Extraction Reagent |
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R401-01 | Vazyme | 100 ml | EUR 133 |
Total RNA Isolation Kit |
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P-9100 | EpiGentek | 50 samples | EUR 347.25 |
Description: The best epigenetics products |
This model system has been very successful in the case of post-mortem tissue because of their relative accessibility to acute brain slices or culture. The current review usage details synaptosomes in AD research and its potential as a valuable tool in furthering our understanding of the pathogenesis and in designing and testing therapeutic strategies for this disease.